ACTIVATORS OF POTASSIUM CHANNELS Russian patent published in 2003 - IPC

FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention relates to pharmaceutical composition comprising pyrrole derivative as active component of the general formula (I) or its pharmaceutically acceptable salt where R¹ represents hydrogen atom or alkoxycarbonyl- amino-group; R² represents alkyl, aryl that can be substituted, aromatic heterocyclyl that can be substituted, unsubstituted amino-group, mono- alkyl-substituted amino-group, dialkyl-substituted amino-group or cyclic amino-group that can be substituted; R³ represents cyano-group or carbamoyl-group; R⁴ represents hydrogen atom or alkyl; E represents alkylene; q = 0 or 1; A means methyl, aryl that can be substituted or aromatic heterocyclyl that can be substituted. This pharmaceutical composition can be used as activator of potassium channels that provides its usage for prophylaxis or treatment of patients with physiological disturbances associated with potassium channels. EFFECT: valuable medicinal properties of compounds. 5 cl, 3 tbl, 4 ex