MEDICINAL AGENT FOR TREATMENT OF CHRONIC ARTICULAR RHEUMATISM Russian patent published in 2006 - IPC A61K31/4412 A61K31/4409 A61K31/4545 A61K31/496 A61K31/5377 A61P19/02 A61P19/04 A61P29/00 

Abstract RU 2282446 C2

FIELD: organic chemistry, medicine, rheumatology.

SUBSTANCE: invention proposes a medicinal agent comprising derivative of aminostilbazol as an active component of the formula : or its salt wherein G represents phenyl optionally substituted with (C1-C6)-alkoxy-group; R represents (1) hydrogen atom, (2) (C1-C6)-hydroxyalkyl, or (3) the group -CORo wherein Ro represents (C1-C6)-alkyl, (C1-C6)-alkoxy-, phenoxy-group. The preferable compound is (E)-4-{2-[2-{N-acetyl-N-[(4-methoxyphenyl)sulfonyl]amino}phenyl]ethenyl}pyridine 1-oxide. The proposed agent is designated for treatment of chronic articular rheumatism.

EFFECT: realization of invention, valuable medicinal properties of agent.

7 cl, 2 tbl, 7 ex

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RU 2 282 446 C2

Authors

Inoue Naoki

Dates

2006-08-27Published

2002-04-09Filed