DERIVATIVES OF AMINOSTILBAZOLE OR THEIR HYDRATES, OR THEIR SALTS AND PHARMACEUTICAL COMPOSITION BASED ON SAID Russian patent published in 1999 - IPC

Abstract RU 2138482 C1

FIELD: organic chemistry. SUBSTANCE: invention relates to derivatives of aminostilbazole of the general formula (I) where R1 or R2 is hydrogen atom; R3,R13 - H, C1-6-alkyl or hydroxy-group; R4,R14 - H, C1-6-alkyl, C1-6-alkoxy-, hydroxy-group, halogen atom or R4,R14 can in common form methylenedihydroxy-group; R5 - H, C1-6-alkyl possibly substituted with halogen atom, amine, mono- or dialkylamino-, morpholino-, alkoxy- or hydroxy-group, C1-6-acyl; R6 - phenylsulfonyl possibly substituted with alkyl, alkoxy-, halogenalkoxy-, hydroxy-, nitro-group or halogen atom; A, B and G - CH, N, N-O, N+-(R7)E- where R7 is C1-6-alkyl or benzyl; E - anion; Y and Z - a ring, or their hydrates or salts that show an anticancer effect. EFFECT: an anticancer effect of compounds. 6 cl, 4 tbl, 59 ex

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RU 2 138 482 C1

Authors

Khirojosi Khidaka

Akira Matsuura

Masato Matsuda

Dates

1999-09-27Published

1995-04-05Filed