PEPTIDE-CONTAINING PREPARATION AND METHOD FOR ITS PREPARING Russian patent published in 2003 - IPC

FIELD: medicine, peptides, pharmacy. SUBSTANCE: invention relates to the development of novel medicinal forms of biologically active peptide compounds. Preparations comprises an active component peptide and protective medium consisting of sucrose, polyglucin, cacao powder, gelatin and ascorbic acid in the following ratio of components, wt.-% per dry matter: gelatin, 16-20; sucrose, 46-52; polyglucin, 6.0-10.0; ascorbic acid, 2.5-3.5; cacao powder, 6.0-8.0; biologically active peptide, the balance. Interferon, insulin, interleukin can be used as a biologically active peptide. Method for preparing the preparation involves mixing peptide with a mixture of sucrose, polyglucin, cacao powder, gelatin and ascorbic acid followed by placing mixture into matrix and tableting by sublimation drying at temperature from 25 to 35 C under pressure 8-15 Pa for at least 48 h. Proposed technology provides the prolonged retention of preparation activity in storage and high effectiveness in therapeutic using. EFFECT: improved preparing method, valuable medicinal properties of preparation. 5 cl, 2 dwg, 2 tbl, 5 ex