STABILIZATION OF COMPOSITIONS "LIPID : DNA" IN SPRAYING PROCESS Russian patent published in 2003 - IPC

Abstract RU 2213578 C2

FIELD: medicine, pharmacy, biotechnology. SUBSTANCE: invention relates to stabilization of "lipid : DNA" in the process of spraying. Invention involves pharmaceutical compound including plasmid DNA carrying gene, cationic lipid, neutral lipid and trypton or glutamic acid and spraying suspension including cationic lipid bis-(guanidinium)-trencholesterol, neutral colipid dioleoylphosphatidylethanolamine or its analogue and plasmid DNA carrying gene also. Invention provides the development of medicinal form used in gene therapy. EFFECT: improved stability, valuable properties of composition. 11 cl, 5 dwg

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RU 2 213 578 C2

Authors

Densmor Charl'Z L.

Najt Dzh. Vernon

Uoldrep Dzh. Klifford

Kinsi Berma M.

Dates

2003-10-10—Published

1999-01-08—Filed