FIELD: organic chemistry, biotechnology, biochemistry. SUBSTANCE: method involves preparing (-)-(cis)-6(S)-phenyl-5(R)-[4-(2-pyrrolidine-1-yl-ethoxy)phenyl] -5,6,7,8- tetrahydronaphthalene-2-ol by effect on racemic mixture of corresponding acetylate with hydrolytic enzyme in the presence of an aqueous buffer solution. Method provides preparing the substance eliciting estrogenic activity. EFFECT: improved preparing method. 13 cl, 1 ex
