FIELD: organic chemistry, medicine, cardiology, pharmacy. SUBSTANCE: invention relates to 4-oxocyclic compounds of urea of the general formula (I) R1,R2,R3,R4,R5, wherein X, Y, R, , A and L are determined in the invention claim. Also, invention describes pharmaceutical composition based on these compounds and method for treatment of arrhythmia and cardiac fibrillation. Invention provides preparing new compounds eliciting valuable biological properties. Invention can be used in medicine as a therapeutic agent for treatment of arrhythmia and cardiac fibrillation. EFFECT: improved treatment method, valuable medicinal properties of compounds. 14 cl, 1 tbl, 66 ex
Title |
Year |
Author |
Number |
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