FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to tricyclic Δ3- piperidines of the general formula (I) Δ3- wherein X means oxygen or sulfur atom; 
means hydrogen atom, halogen atom, R1-alkyl or C1-6-alkyloxy-group; Alk means C1-4-alkanediyl; D is given in the invention claim. Invention describes also methods for preparing compounds of the formula (I) and a pharmaceutical composition eliciting an antagonistic activity with respect to the central C1-6-adrenoreceptor based on these compounds. Invention provides preparing new compounds exhibiting valuable biological properties. EFFECT: improved preparing methods, valuable medicinal properties of compounds. 11 cl, 17 dwg, 5 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| BENZOTHIENO[3,2-C]PYRIDINES, METHOD FOR THEIR PREPARING (VARIANTS), PHARMACEUTICAL COMPOSITION AND METHOD FOR ITS PREPARING | 1999 |
|
RU2222542C2 |
| TRICYCLIC ?3-PIPERIDINES, METHODS FOR THEIR PREPARING AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 1999 |
|
RU2230744C2 |
| DERIVATIVES OF THIADIAZOLYLPYRIDAZINE INHIBITING ANGIOGENESIS, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING | 1998 |
|
RU2194049C2 |
| HETEROCYCLYLAMINOALKYL-SUBSTITUTED BENZIMIDAZOLES | 2006 |
|
RU2419613C2 |
| 2-SUBSTITUTED BENZIMIDAZOLES | 2006 |
|
RU2441866C2 |
| DERIVATIVES OF 1,2,3,4-TETRAHYDROBENZOFURO[3,2-C]-PYRIDINE, METHODS OF THEIR SYNTHESIS AND COMPOSITIONS BASED ON THEREOF | 1998 |
|
RU2198175C2 |
| DERIVATIVES OF PYRROLEQUINOLINONE, METHOD OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS FOR THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING | 1994 |
|
RU2129554C1 |
| TRICYCLIC LACTAM DERIVATIVES AS 11-β-HYDROXYSTEROID DEHYDROGENASE INHIBITORS | 2005 |
|
RU2386617C2 |
| AMINOBENZIMIDAZOLES AND BENZIMIDAZOLES AS INHIBITORS OF REPLICATION OF RESPIRATORY SYNCYTIAL VIRUS | 2004 |
|
RU2379302C2 |
| HIV-INHIBITING 5-CARBO- OR HETEROCYCLIC SUBSTITUTED PYRIMIDINES | 2005 |
|
RU2403244C2 |
