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2 227 140

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IPC

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Application

2002128129/04, 2002-10-22

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Start date

2002-10-22

(22)

Actual filing date

2002-10-22

(45)

Published

2004-04-20

(72)

Inventor

Alferov A.V.Severin E.S.Krjukov L.N.Panov A.E.Vorontsov E.A.Kuznetsov S.L.Mikerin I.E.

(73)

Holder

Zakrytoe Aktsionernoe Obshchestvo

METHOD FOR PREPARING SEROTONIN AND ITS PHARMACOLOGICAL SALTS Russian patent published in 2004 - IPC

Abstract RU 2227140 C1

FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to method for preparing serotonin and its water-soluble pharmacologically acceptable salts. Method involves reduction of 5-benzyloxytryptamine or 5-benzyloxy-3-(2-nitroethyl)-indole in hydrogen flow in the presence of 10% palladium on activated carbon as a catalyst. Process is carried out under pressure 20-30 atm. Method provides preparing end products with the yield 90-97%. EFFECT: improved preparing method, high yield. 3 cl, 5 sch, 4 ex

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RU 2 227 140 C1

Authors

Alferov A.V.

Severin E.S.

Krjukov L.N.

Panov A.E.

Vorontsov E.A.

Kuznetsov S.L.

Mikerin I.E.

Dates

2004-04-20—Published

2002-10-22—Filed