METHOD FOR PREVENTION ABUSE WITH OPIOID- -CONTAINING MEDICINAL FORMULATIONS Russian patent published in 2004 - IPC

FIELD: medicine, narcology. SUBSTANCE: invention relates to method for diminishing the possibility for abuse with oral medicinal formulation of opioid analgetic wherein analgetically active amount of orally active opioid agonist is combined with opioid antagonist to obtain a medicinal formulation for oral using. At least two-step extraction is required for isolation opioid agonist and amount of opioid antagonist added to a medicinal formulation is sufficient to suppress effect of opioid in combined extraction with opioid agonist and parenteral administration. Invention provides aversion effect in cases when the large dose of product is used by a person with the formed physical dependence. EFFECT: improved preventing method. 58 cl, 4 tbl, 3 ex