MATRIX PROVIDING PROLONGED, INVARIANT, AND INDEPENDENT RELEASING OF ACTIVE SUBSTANCES Russian patent published in 2007 - IPC A61K31/485 A61K9/26 A61P25/04 A61P25/36

Abstract RU 2297225 C2

FIELD: pharmaceutical industry.

SUBSTANCE: invention relates to composition containing at least two active ingredients, opioid analgesic, and opioid agonist in non-swelling diffusive matrix. Releasing characteristics are defined by matrix made of ethylcellulose and at least one fatty alcohol. Also disclosed is pharmaceutical preparation containing 10-150 mg of oxycodone and 1-50 mg of naloxone in standard dose.

EFFECT: composition of long storage time with prolonged invariant and independent releasing of substances.

17 cl, 14 dwg, 16 ex, 19 tbl

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RU 2 297 225 C2

Authors

Bregmann Bianka

Mjukhlau Zilke

Shpittslej Kristof

Dates

2007-04-20—Published

2003-04-04—Filed