MEDICINAL AGENT AS RAW FOR MANUFACTURING RAPIDLY HELPING NITROGLYCERIN-BASE PREPARATIONS AND METHOD FOR ITS PREPARING Russian patent published in 2004 - IPC

Abstract RU 2228748 C1

FIELD: medicine, chemical-pharmaceutical industry, pharmacy. SUBSTANCE: invention relates to compositions designated for manufacturing rapidly helping nitroglycerin-base preparations. Invention describes the composition of nitroglycerin with glucose representing glucose crystalline structure wherein its pores are filled with nitro- Glycerin being nitroglycerin is distributed by deep of glucose crystal. Method for preparing involves preparing raw, sorption of glucose with nitroglycerin solution in polar organic solvent and drying the prepared mass. Sorption of nitroglycerin with glucose is carried out in ethyl acetate or butyl acetate, or amyl acetate medium in static state and at stirring. Then distillation off under vacuum is carried out that provides boiling a solvent, removal of residual solvent followed by stabilization of dry mass at stirring. Method exhibits less labor intensity and provides preparing the explosion-proof composition wherein no nitroglycerin exudation occurs. EFFECT: improved preparing method. 6 cl, 3 dwg, 1 ex

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RU 2 228 748 C1

Authors

Milekhin Ju.M.

Pankova E.V.

Minakov O.Eh.

Dates

2004-05-20Published

2003-07-03Filed