FIELD: biotechnology, molecular biology, biochemistry. SUBSTANCE: invention relates to 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase and DNA fragment encoding this enzyme. 3-Deoxy-D-arabinoheptulosonate 7-phosphate synthase is isolated from Methylophilus methylotrophus cells and can comprise substitutions, deletions, insertions or additions of one or some amino acids in amino acid sequence but with retention of its enzymatic activity. This enzyme plays the key role in biosynthesis of aromatic compounds, such as L-phenylalanine, L-tyrosine and L-tryptophan. Invention provides improving the productivity of L-amino acids due to the enhancement of activity of enzymes involved in biosynthesis ways of L-amino acids. EFFECT: valuable properties of enzyme. 3 cl, 2 tbl, 2 dwg
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