FIELD: organic chemistry, medicine, biochemistry, pharmacy.
SUBSTANCE: invention relates to a method for inhibition of RAF kinase-mediated growth of tumor cells that involves administration of derivatives of substituted urea of the formula (I):
heterocyclic derivatives of urea of the formula (I) and pharmaceutical composition comprising derivatives of urea of the formula (I). Invention provides enhanced effectiveness of inhibition.
EFFECT: improved inhibition method, valuable medicinal properties of compounds.
79 cl, 5 tbl, 58 ex
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Authors
Dates
2004-07-10—Published
1998-12-22—Filed