METHOD FOR INHIBITION OF RAF KINASE-MEDIATED GROWTH OF TUMOR CELLS, HETEROCYCLIC UREA DERIVATIVES (VARIANTS), PHARMACEUTICAL COMPOSITION (VARIANTS) Russian patent published in 2004 - IPC

Abstract RU 2232015 C2

FIELD: organic chemistry, medicine, biochemistry, pharmacy.

SUBSTANCE: invention relates to a method for inhibition of RAF kinase-mediated growth of tumor cells that involves administration of derivatives of substituted urea of the formula (I):

heterocyclic derivatives of urea of the formula (I) and pharmaceutical composition comprising derivatives of urea of the formula (I). Invention provides enhanced effectiveness of inhibition.

EFFECT: improved inhibition method, valuable medicinal properties of compounds.

79 cl, 5 tbl, 58 ex

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RU 2 232 015 C2

Authors

Vud Dzhil Eh.

Dzhonson Dzhefri

Djuma Zhak

Kajre Judehj

Li Uehndi

Louinger Timoti Bruno

Paul'Sen Khol'Ger

Redmehn Aniko

Renik Dzhouehl

Ridl' Bernd

Sibli Robert

Skott Uil'Jam Dzh.

Smit Rodzher Eh.

Khatoum-Mokdad Kholija

Dates

2004-07-10Published

1998-12-22Filed