FIELD: organic chemistry, chemical technology.
SUBSTANCE: invention describes dimeric amphiphiles of the general formula (I) $$$ wherein R1 and R2 are similar or can differ of one another and mean saturated or unsaturated hydrocarbon (C12-C22)-chain; R3 and R4 are similar or can differ of one another and mean lower alkyl; R5 can mean the following values: saturated (C3-C22)-chain; residue of mono-, di- or triethylene glycol, cystine residue; n and m are similar or can differ of one another and mean a whole number from 1 to 3; X' and Y; are similar or can differ of one another and mean nontoxic anions used as agents for transfection. Invention describes also a method for preparing such compounds that involves alkylation of free amino-group in amino acid diether to tertiary amino-group by interaction with formalin in the presence of 80-85% formic acid and binding two molecules of diether using active derivative of the corresponding spacer in medium of polar aprotonic organic solvent.
EFFECT: improved preparing method.
3 cl, 7 ex
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