METHOD FOR TREATING RECTAL CANCER Russian patent published in 2004 - IPC

FIELD: medicine, oncology.

SUBSTANCE: the present innovation deals with methods of combined therapy in oncological patients. The method deals with affecting a tumor with distance gamma-radiation, local UHF-hyperthermia and intra-intestinal injection of composite mixture followed by operative interference. On the 1^st d of 5-d-long course of radiation patients undergoes a seance of distance gamma-therapy ROD - 5 Gr. On the 2^nd and 4^th d one should intrarectally introduce a composite mixture containing metronidasol, sodium alginate and 2%-dimethylsulfoxide solution at the following ratios of ingredients, weight%: metronidasol 12-22, sodium alginate 4-6, dimethylsulfoxide 2, distilled water - up to 100. After 6-h-long exposure comes seance of distance gamma-therapy ROD - 5 Gr, moreover, on the 4^th d - with subsequent local UHF-hyperthermia at 42.5-43 C for 60 min. On the 3d and 5^th d it is necessary to conduct analogous seances of local UHF-hyperthermia followed by those of distance gamma-therapy ROD - 5 Gr. The method enables to enhance damaging action of preoperational irradiation upon a tumor by providing maximum radiosensitizing effect and decrease the frequency of locoregional relapses.

EFFECT: higher efficiency of therapy.

1 cl, 1 dwg, 2 ex