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2 424 011

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IPC

A61N5/10(2006-01-01)

A61N2/04(2006-01-01)

A61K31/51(2006-01-01)

A61K31/41(2006-01-01)

A61K31/10(2006-01-01)

A61P5/00(2006-01-01)

(21) (22)

Application

2010105640/15, 2010-02-18

(24)

Start date

2010-02-18

(22)

Actual filing date

2010-02-18

(45)

Published

2011-07-20

(72)

Inventor

Barsukov Jurij AndreevichOltarzhevskaja Natalija DmitrievnaTkachev Sergej IvanovichNikolaev Andrej Vasil'EvichKorovina Marija Anatol'EvnaAliev Vjacheslav AfandievichKuz'Michev Dmitrij VladimirovichGlebovskaja Valerija VladimirovnaGradjushko Aleksandr TikhonovichJagubov Sergej ArkadievichPavlova Anna Mikhajlovna

(73)

Holder

Uchrezhdenie Rossijskoj Akademii Meditsinskikh Nauk Rossijskij Onkologicheskij Nauchnyj Tsentr Imeni N.N. Blokhina Ramn Im. N.N. Blokhina Ramn)Obshchestvo S Ogranichennoj Otvetstvennost'Ju Ob"Edinenie Tekstil'Progress Inzhenernoj Akademii" Tekstil'Progress Inzhenernoj Akademii")

METHOD OF TREATING RECTAL CANCER Russian patent published in 2011 - IPC A61N5/10 A61N2/04 A61K31/51 A61K31/41 A61K31/10 A61P5/00

Abstract RU 2424011 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to oncology, and can be applied in treating rectal cancer (RC). A method involves the intrarectal introduction of 5-fluorouracil and metronidazole in a composite mixture containing sodium alginate and 2 % dimethylsulphoxide, beam therapy, local SHF hyperthermia followed by a surgical intervention. 5-fluorouracil is introduced daily from the 1^st to 5^th day, and from the 3^rd and 5^th days of the therapeutic course, 5-ftoruratsil is introduced in a combination with metronidazole with the exposition 5 hours, and the surgical intervention follows in 2-3 weeks after the therapeutic course.

EFFECT: use of the invention allows increasing recurrence-free survival rate in the RC patients.

2 ex

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RU 2 424 011 C1

Authors

Barsukov Jurij Andreevich

Oltarzhevskaja Natalija Dmitrievna

Tkachev Sergej Ivanovich

Nikolaev Andrej Vasil'Evich

Korovina Marija Anatol'Evna

Aliev Vjacheslav Afandievich

Kuz'Michev Dmitrij Vladimirovich

Glebovskaja Valerija Vladimirovna

Gradjushko Aleksandr Tikhonovich

Jagubov Sergej Arkadievich

Pavlova Anna Mikhajlovna

Dates

2011-07-20—Published

2010-02-18—Filed