THERAPY OF RECTAL CANCER Russian patent published in 2009 - IPC A61N5/10 A61K31/513 A61K31/4164 A61K31/734 A61K31/10 A61P1/00 A61P35/00 A61N7/02 

FIELD: medicine.

SUBSTANCE: therapy of rectal cancer is ensured by preoperative beam therapy "РОД" 5 Gy during 5 days, in combination with local microwave hyperthermia at temperature 42.5-43°C during 60 minutes for 3, 4 and 5 days after beam therapy sessions. A composite mixture containing sodium alginate, 2% dimethyl sulfoxide and 5-fluorouracil is introduced through rectum at exposition 6 hours in 1, 2 and 4 days prior to beam therapy sessions. For 3 and 5 days, at the same exposition, said composite mixture containing metronidazole instead of 5-fluorouracil is introduced. Further, surgical procedure follows.

EFFECT: due to selected introduction regiment of chemotherapeutical preparations as parts of the composite mixture, the method provides high concentration thereof in rectal tumours without side effect, ensures high degree of beam pathomorphism in vast majority of the patients of said category, the absence of recurrent tumour and dissemination within 3 postoperative years.

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