METHOD OF TREATING SQUAMOUS CELL CANCER OF ANAL CANAL Russian patent published in 2011 - IPC A61N5/06 A61B18/18 A61B18/04 A61K31/4164 A61K31/282 A61K31/7052 A61P35/00 

Abstract RU 2427399 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, oncology, and can be used for treating squamous cell cancer of anal canal. That is ensured by two-stage therapy every 2-3 weeks. The I stage involves beam therapy on the area of small pelvis: a primary tumour, pararectal, pelvic, inguinal lymph nodes from both sides. A single basic dose is 2 Gy for 20 sessions to total basic doses 44 Gy. Starting with the 9th sessions of beam therapy, the radiation fraction is preceded with 5 sessions of local electromagnetic hyperthermia. On the 2nd and 4th days of local electromagnetic hyperthermia sessions, metronidazole as an ingredient of a composite mixture is introduced through rectum with exposition 5 hours before radiation. On the days of the introduction of metronidazole, local electromagnetic hyperthermia follows the radiation fraction with single basic dose 4 Gy.

EFFECT: method allows avoiding a surgery, namely combined abdominoperineal resection, increasing recurrence-free survival rate and improving quality of life of the patients.

2 cl, 1 tbl, 2 ex

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Authors

Tkachev Sergej Ivanovich

Barsukov Jurij Andreevich

Glebovskaja Valerija Vladimirovna

Timofeev Jurij Mikhajlovich

Tsarjuk Vladimir Fedorovich

Malikhov Andrej Gennad'Evich

Sakharovskaja Violeta Grigor'Evna

Zavistovskij Andrej Valer'Evich

Gutnik Raisa Andreevna

Kim Dmitrij Feliksovich

Dates

2011-08-27Published

2009-12-16Filed