FIELD: medicine, biotechnology.
SUBSTANCE: the present innovation deals with manufacturing curative-prophylactic preparations based upon human recombinant alpha-2-interferon for injections in dry lyophilized form. This preparation includes substance of human recombinant alpha-2-interferon, saline buffer system and stabilizing additive containing plasma-substituting solution, multi-atomic alcohol and either urea or EDTA. As plasma-substituting solution this preparation contains polyglucin, or rheopolyglucin, or hemodesis, or mixture of mentioned components at 1:1:1 ratio. Thus, the preparation has been developed which could be stored at above 4 C, for example, at room temperature (20 + 3 C).
EFFECT: higher efficiency.
3 cl, 10 ex, 2 tbl
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Authors
Dates
2004-09-27—Published
2002-05-06—Filed