FIELD: medicine.
SUBSTANCE: method involves determining availability of p53 gene in /+(O/R) genotype from allelic polymorphism in Bam HI RELP restrictase recognition site in 5 exon of this gene. The gene being found, large-scale ischemic brain lesion (greater than 90 cm3) is predicted with probability greater than 75% in the cases of blood supply disorder under minimum probability of small-scale (below 40 cm3) infarctions.
EFFECT: high accuracy in determining persons of high sensitivity among practically health people.
1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTING THE SCOPE OF CEREBRAL INFARCTION IN CASE OF ACUTE DISORDERS OF CEREBRAL CIRCULATION | 2002 |
|
RU2238557C2 |
| ALLELE S608L (150S/T) OF GENE NOS2, APPLICATION THEREOF FOR PREDICTION OF COURSE OF ACUTE ATHEROTHROMBOTIC ISCHEMIC STROKE FORMATION, APPLICATION AS MOLECULAR GENETIC MARKER OF INDIVIDUAL CEREBRAL TISSUE SENSITIVITY TO ISCHEMIA AND METHOD FOR PREDICTION OF COURSE OF ACUTE ISCHEMIC ATHEROTHROMBOTIC STROKE | 2010 |
|
RU2423523C1 |
| PHARMACEUTICAL COMPOSITION FOR TREATING ISCHEMIC INSULT AND METHOD FOR THERAPY | 2002 |
|
RU2251429C2 |
| METHOD FOR PREDICTING THE OUTCOME OF ISCHEMIC STROKE | 2018 |
|
RU2703474C1 |
| METHOD OF TREATING PATIENTS WITH ISCHEMIC STROKE IN EARLY PERIOD OF DISEASE | 2020 |
|
RU2742746C1 |
| METHOD FOR BRAIN PROTECTION IN CASE OF CAROTID RECONSTRUCTION DURING ACUTE ISCHEMIC STROKE | 2016 |
|
RU2614270C1 |
| METHOD OF PREDICTING OUTCOME OF CARDIOCEREBRAL PATHOLOGY IN PATIENTS WITH DIABETES MELLITUS | 2009 |
|
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| DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR ARTERIAL AND VENOUS ISCHEMIC STROKES | 2015 |
|
RU2606597C1 |
| METHOD FOR PREDICTION OF RISK OF EMBOLOGENIC RAPTURE OF CAROTID ATHEROSCLEROTIC PLAQUE | 2019 |
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RU2729733C1 |
| METHOD FOR PREDICTING EMBOLIC HAZARD OF UNSTABLE CAROTID ATHEROSCLEROTIC PLAQUE | 2019 |
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RU2723741C1 |
