FIELD: medicine, pharmaceutical industry, pharmacy.
SUBSTANCE: invention relates to manufacturing medicinal agents used in cold diseases, for headache relief and in neuralgia. Analgetic antipyretic medicinal agent comprises acetylsalicylic acid, paracetamol, caffeine, cacao, starch, citric acid, refined sugar, talc, calcium stearate and can comprises polyvinylpyrrolidone with molecular mass 9900-35500 Da additionally in the definite ratio of components. Method for preparing new agent involves preparing raw, preparing mass for tabletting by mixing paracetamol, starch, caffeine, cacao, wetting the prepared mass with 45-50% citric acid solution, 4.5-7.5% starch sizing and 10-80% sugar syrup or 45-50% citric acid solution and 10-80% sugar syrup, wet granulation, drying, powdering with acetylsalicylic acid, starch, talc and calcium stearate and dry granulation followed tabletting the prepared mass.
EFFECT: improved preparing method, enhanced strength of tablets.
5 cl, 1 tbl
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Authors
Dates
2004-11-27—Published
2002-11-04—Filed