FIELD: organic chemistry, medicine, gastroenterology, pharmacy.
SUBSTANCE: invention relates to heterocyclic compounds with substituted phenyl group of the formula (I):
or their pharmaceutically acceptable salt wherein R1 represents (C1-C6)-alkyl; R2 represents (C1-C6)-alkyl; R3 represents hydrogen (H) or halogen atom and
represents the substituted heterocycle as given in cl. 1 of invention claim; X represents NH or oxygen atom (O). Also, invention relates to a method for preparing compounds of the formula (I) and to pharmaceutical preparations for their applying in inhibition of gastric acid secretion based on these compounds. Invention provides preparing new compounds and pharmaceutical preparations based on thereof eliciting an anti-inflammatory activity with respect to gastroenteric diseases.
EFFECT: improved preparing method, valuable medicinal properties of compounds and preparations.
16 cl, 4 ex
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