FIELD: organic chemistry, medicine, gastroenterology. SUBSTANCE: invention relates to novel derivatives of imidazo[1,2-a]pyridine of the formula (I) 
or its pharmaceutically acceptable salts where R1 means CH3 or CH2OH; R2 and R3 mean lower alkyl; R4 means H or halogen atom; R5 means h<halogen atom or lower alkyl; X means NH or O. Compounds of the formula (I) inhibit secretion of gastric acid and can be used for treatment of gastroenteric inflammatory diseases. EFFECT: improved method of synthesis, valuable medicinal properties. 35 cl, 4 tbl, 58 ex
| Title |
Year |
Author |
Number |
| NOVEL COMPOUNDS |
1997 |
- Amin Kosrat
- Dakhl'Strem Mikaehl'
- Nordberg Peter
- Starke Ingemar
|
RU2184113C2 |
| THROMBIN INHIBITORS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF, METHOD OF TREATMENT, METHOD OF THEIR SYNTHESIS (VERSIONS) AND PROTECTED DERIVATIVE |
1996 |
- Gustafsson David
- Njustrem Jan-Ehrik
|
RU2176645C2 |
| 4-AMINO-3-ACYLQUINOLINE DERIVATIVES, METHOD OF PREPARATION THEREOF, PHARMACEUTICAL AGENT BASED THEREOF, METHOD OF PREPARATION OF PHARMACEUTICAL AGENT, AND INTERMEDIATE COMPOUND |
1994 |
|
RU2142454C1 |
| THROMBIN INHIBITOR-CONTAINING AQUEOUS SOLUTION FOR NONPARENTERAL ADMINISTRATION SHOWING STABILITY AT STORAGE |
1995 |
- Ulla St'Ernfel'T
- Mats Sundgren
|
RU2164803C2 |
| METHOD FOR PREPARING SUBSTITUTED IMIDAZOPYRIDINE |
2001 |
- Ehl'Man B'Ern
- Ehrbak Sil'Ke
- Timermann Ehrik
|
RU2275372C2 |
| PHENOXYPYRIDINYLAMIDE DERIVATIVES, AND THEIR USE IN TREATMENT OF PDE4-MEDIATED DISEASE STATES |
2009 |
- Ehndrjus Glen
- Koks Rona Dzhejn
- De Savi Kristofer
- Megani Premdzhi
- Sangani Khitesh Dzhajantilal
- Uorner Daniehl' Dzhon
|
RU2509077C2 |
| PEPTIDE DERIVATIVES, THEIR STEREOISOMERS OR PHYSIOLOGICALLY ACCEPTABLE SALTS SHOWING ANTITHROMBOSIS, ANTICOAGULATING OR ANTI-INFLAMMATORY ACTIVITY, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF SUPPRESSION OF THROMBIN ACTIVITY, METHOD OF INHIBITION OF KININOGENASES ACTIVITY, USE OF COMPOUNDS AS PARENT SUBSTANCES FOR SYNTHESIS OF THROMBIN INHIBITOR |
1994 |
- Karl Tomas Antonsson
- Rut Ehl'Vju Bjulund
- Nil'S David Gustafsson
- Nil'S Olov Ingemar Nil'Sson
|
RU2142469C1 |
| DERIVATIVES OF IMIDAZOPYRIDINE, METHOD FOR THEIR PREPARING AND INTERMEDIATE COMPOUNDS, PHARMACEUTICAL PREPARATION BASED ON THEREOF (VARIANTS), METHOD FOR INHIBITION OF GASTRIC ACID SECRETION AND METHOD FOR TREATMENT OF STATES ASSOCIATED WITH HELICOBACTER PYLORI INFECTION |
1999 |
- Amin Kosrat
- Dal'Strem Mikaehl'
- Nordberg Peter
- Starke Ingemar
|
RU2235725C2 |
| PIPERIDINE DERIVATIVES |
2011 |
- Baumann Karlkhajnts
- Flor Aleksandr
- Getshi Ehrvin
- Grin Ljuk
- Zholidon Siniz
- Knust Khenner
- Limberg An'Ja
- Luehbbers Tomas
- Tomas Ehndrju
|
RU2554353C2 |
| DIHYDROPYRIDINES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION BASED ON SAID AND METHOD OF BLOOD PRESSURE DECREASE |
1994 |
- Chell' Jal'Mar Andersson
- Margareta Nordlander
- Rol'F Krister Vesterlund
|
RU2139278C1 |
