FIELD: organic chemistry, chemical technology, medicine.
SUBSTANCE: invention relates to (DL)-1-hydroxy-3,7,7,9,9-pentamethyl-1,4,8-triazaspiro[4,5]decane-2-one of the formula (1)
.
Also, invention describes a method for preparing this compound by treatment of DL-alanine hydroxamic acid with ketone wherein aminoketone - 2,2,6,6-tetramethylpiperidine-4-one is used as ketone, and process is carried out in benzene medium in the mole ratio of reagents: α-aminohydroxamic acid : aminoketone = 1:1.1 followed by isolation of the end product. Invention provides preparing new compound that can be used as a nontoxic antimetastatic medicinal agent.
EFFECT: improved preparing method, valuable medicinal properties of compound.
3 cl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PROCESS ADDITIVES AND USE THEREOF IN ROTARY MOULDING | 2011 |
|
RU2597918C2 |
| PROCESS ADDITIVES AND THEIR USE IN ROTARY MOLDING | 2011 |
|
RU2742578C2 |
| STABILISER COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND METHODS OF USE | 2013 |
|
RU2662823C2 |
| STABILISATION OF ORGANIC MATERIAL WITH MANNICH COMPOUNDS BASED ON AMINOTRIAZINE | 2012 |
|
RU2593997C2 |
| METHOD FOR PHOTOCHEMICAL HARDENING LIGHT-EMITTING DIODES | 2005 |
|
RU2396287C2 |
| CONCENTRATED FORMS OF WATER-BASED LIGHT-STABILISERS MADE BY HETEROPHASE POLYMERISATION TECHNIQUE | 2004 |
|
RU2354664C2 |
| STABILIZED POLYOLEFIN OBTAINED BY ROTATIONAL MOULDING | 2019 |
|
RU2831778C2 |
| METHOD FOR DECREASING POLYPROPYLENE MOLECULAR MASS | 2001 |
|
RU2298563C2 |
| POLYPROPYLENE COMPOSITION | 2019 |
|
RU2815313C2 |
| STABILIZED POLYMER COMPOSITION, STABILIZER CONTAINED THEREIN, AND A METHOD FOR PREPARATION THEREOF | 1998 |
|
RU2230758C2 |
Authors
Dates
2004-12-27—Published
2003-07-25—Filed