FIELD: biotechnology.
SUBSTANCE: fusion protein (F), attachment protein (G) and matrix protein (M) of respiratory-syncytial virus are isolated from respiratory-syncytial virus by extraction of proteins with weak detergent from concentrated virus and purified by column chromatography method using column with hydroxyapatite or other carrier and by elution of protein using mild saline treatment. Proteins F, G and M prepared as immunogenic compositions show safety and high immunogenic activity.
EFFECT: improved preparing method, valuable properties of proteins.
18 cl, 9 tbl, 4 dwg
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