STRAIN OF LACTOBACILLI LACTOBACILLUS PARACASEI CNCM I-2116 (NCC 2461) ELICITING ABILITY TO PREVENT INTESTINE COLONIZATION WITH PATHOGENIC MICROORGANISMS CAUSING DIARRHEA, SUPERNATANT OF ITS CULTURE AND ORAL AGENT FOR PROPHYLAXIS AND/OR TREATMENT OF DIARRHEA-ASSOCIATED DISORDERS Russian patent published in 2005 - IPC

FIELD: biotechnology, microbiology, medicine.

SUBSTANCE: invention relates to the strain Lactobacillus paracasei CNCM I-2116 used for diarrhea prophylaxis causing by pathogenic microorganisms. Supernatant of this strain culture elicits ability to prevent colonization of intestine with pathogenic microorganisms causing diarrhea also and this strain is designated for preparing agent used for prophylaxis and/or treatment of disorders associated with diarrhea. Agent for oral administration represents therapeutically effective dose of the strain L. paracasei CNCM I-2116 or supernatant of its culture and acceptable foodstuff. Invention provides the enhanced viability of the strain in its applying and effectiveness in prophylaxis of adhesion to intestine cells and invasion to intestine cells of pathogenic microorganisms causing diarrhea.

EFFECT: valuable medicinal properties of strain.

5 cl, 8 dwg, 10 ex