FIELD: medicine, pharmaceutics.
SUBSTANCE: described are immunogenic peptides, compositions and methods of their application for therapeutic-prophylactic purposes and/or reduction of intensity against infectious disease, caused by influenza virus, containing two amino acid sequences, different from each other. Described is isolated polynucleotide, which codes immunogenic peptide. Invention includes isolated antibody, specific with respect to peptide. Composition by the invention based on immunogenic peptide is applied for obtaining medication or vaccine. Methods by the invention deals with induction of immunologic response against influenza virus, prevention or control of infection outbreak, cased by influenza virus, in population of mammals, and induction of protective immune response against influenza virus in mammals.
EFFECT: invention ensures efficient compositions and improved delivery of therapeutic and/or preventive medications to mammals.
15 cl, 30 dwg, 15 tbl, 10 ex
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Authors
Dates
2012-11-27—Published
2008-08-27—Filed