PEPTIDE COMPOSITION ELICITING IMMUNITY REGULATING PROPERTY Russian patent published in 2005 - IPC

Abstract RU 2244719 C1

FIELD: medicine, immunology, peptides.

SUBSTANCE: invention relates to a new composition of biologically active substances. Invention proposes the composition comprising of peptides of the formula: Arg-Gly-Asp and H-Tyr-X-Y-Glu-OH wherein X means Gln and/or Glu; Y means Cys(acm) and/or Cys that elicits ability to inhibit the proliferative response for phytohemagglutinin, to induce the suppressive activity of mononuclear cells and ability of peptides to induce secretion of immunosuppressive cytokines of grouth-transforming factor-β1 and interleukin-10 (IL-10). The composition can be prepared by a simple procedure.

EFFECT: valuable biological properties of composition.

3 cl, 16 tbl, 9 ex

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RU 2 244 719 C1

Authors

Terent'Ev A.A.

Alikhanov Kh.A.

Kacharava Leonid Jazonovich

Dates

2005-01-20Published

2003-07-29Filed