PEPTIDE COMPOSITION POSSESSING IMMUNOREGULATORY PROPERTY Russian patent published in 2005 - IPC

Abstract RU 2266297 C1

FIELD: medicine, chemistry of peptides, amino acids.

SUBSTANCE: invention relates to novel biologically active substances. Invention proposes the novel composition comprising peptides of the formula: H-Arg-Gly-Asp-OH and H-Tyr-X-Y-Glu-OH wherein X means Gln and/or Glu; Y means Cys(acm) and/or Cys. The composition shows ability to inhibit proliferative activity of mononuclear cells, to induce suppressive activity and their ability for secretion of cytokines TNF-1β (tumor necrosis factor-1β) and IL-10 (interleukin-10 ).

EFFECT: simplified method for preparing composition, valuable medicinal properties of composition.

4 cl, 16 tbl, 9 ex

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RU 2 266 297 C1

Authors

Terent'Ev A.A.

Alikhanov Kh.A.

Kacharava Leonid Jazonovich

Dates

2005-12-20Published

2004-05-12Filed