POLYVALENT BINDING PROTEINS FOR ACTIVATION OF NATURAL KILLER CELLS AND THEIR THERAPEUTIC APPLICATION FOR TREATMENT OF MALIGNANT NEOPLASM Russian patent published in 2023 - IPC C07K16/18 C07K16/28 C07K16/30 C07K19/00 C12N15/113 A61K35/17 A61K38/17 

Abstract RU 2809125 C2

FIELD: biochemistry.

SUBSTANCE: polyvalent binding protein that binds to NKG2D, CD16 and tumor-specific antigen. Also a pharmaceutical composition containing this protein is presented. A method for enhancing the death of tumor cells; method for treating malignant neoplasms are disclosed.

EFFECT: effective treatment of malignant neoplasms.

16 cl, 9 tbl, 70 dwg, 17 ex

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RU 2 809 125 C2

Authors

Chang, Gregory, P.

Cheung, Ann, F.

Haney, William

Grinberg, Asya

Dates

2023-12-07Published

2018-02-08Filed