FIELD: organic synthesis.
SUBSTANCE: invention relates to a novel method fir preparing fluorinated methylbenzyl alcohol depicted by formula 2:
, where m represents integer from 0 to 3 and m+n the same from 1 to 4, which can find use as starting or intermediate material for synthesis of medical and pharmaceutical products as well as agricultural chemicals. Method comprises catalytic hydrogen-mediated hydrogenolysis of one hydroxyl group in fluorinated benzene dimethylolbenzene depicted by formula 1:
, where m and n are as above, carried out in solvent. Method is industrially acceptable.
EFFECT: expanded synthetic possibilities.
13 cl, 5 ex
Title |
Year |
Author |
Number |
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2001 |
- Murakami Masatoshi
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- Morikava Kokhej
|
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|
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|
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|
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0 |
- Shtark Aleksandr Antonovich
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|
SU1016275A1 |