METHOD FOR PREPARING BACTERIAL RADIOPHARMACEUTICAL PREPARATION Russian patent published in 2005 - IPC

Abstract RU 2255748 C2

FIELD: medicine, experimental medicine, pharmacy.

SUBSTANCE: method involves culturing microorganism Escherichia coli on the nutrient medium agar-agar under aerobic conditions followed by addition of mixture containing Tc99m-pertechnatat, human albumin solution, physiological solution and culturing under anaerobic conditions. The prepared bacterial-isotope complex is subjected for dialysis for five stages. Method provides enhancing the lifetime content of isotope in the bacterial radiopharmaceutical preparation up to 77.7 MBk (62.9-92.5) in 1 ml wherein impurity of free technetium is 5%, not above. Method can be realized in small laboratory animals.

EFFECT: improved method for preparing.

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RU 2 255 748 C2

Authors

Kuvshinov A.G.

Il'Icheva E.A.

Lepekhova S.A.

Shameev A.Ju.

Chikoteev S.P.

Koval' E.V.

Fadeeva T.V.

Maksikov D.I.

Galeev Ju.M.

Popov M.V.

Dates

2005-07-10Published

2003-05-26Filed