FIELD: chemistry.
SUBSTANCE: method includes preparing tin (II) chloride dihydrate solution, mixing with powdered doxorubicin hydrochloride with addition of 1 ml of a buffer solution at pH 4.01, freezing the obtained mixture at liquid nitrogen temperature, freeze drying at 50°C at pressure of 0.0015 Torr for not less than 20.5 hours, followed by final drying for not less than 5.5 hours at +16±2°C.
EFFECT: invention enables to stabilise pH of the reagent for producing technetium-99m labelled doxorubicin.
1 dwg
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