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Application

2003135173/13, 2003-12-04

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Start date

2003-12-04

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Actual filing date

2003-12-04

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Published

2005-08-10

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Inventor

Krasnjanskij V.P.Mikhajlov V.V.Borisevich I.V.Potryvaeva N.V.Mel'Nikov S.A.Timan'Kova G.D.

(73)

Holder

Virusologicheskij Tsentr Nii Mikrobiologii Ministerstva Oborony Rossijskoj Federatsii

LIQUID PREPARATION CONTAINING IMMUNOGLOBULIN EFFICIENT AGAINST MARBURG FEVER FROM HORSE BLOOD SERUM (HORSE IMMUNOGLOBULIN MARBURG) Russian patent published in 2005 - IPC

Abstract RU 2257916 C1

FIELD: clinical immunology.

SUBSTANCE: preparation represents 9.0-11.0% solution of horse blood serum immunoglobulins with pH 7.0-7.5 and content of γ-immunoglobulin fraction at least 90.0% of the total protein. Nonspecific fractions in preparation are albumin, α- and β-globulin fractions in amount not larger than 10.0%, and residual ethyl alcohol in amount not larger than 4.0%. Preparation is characterized by virus-neutralizing antibodies against virus Marburg. Titer of virus-neutralizing antibodies is at least 1:2048 and can be used for emergency prevention of Marburg fever in humans.

EFFECT: extended immunoglobulin application area.

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RU 2 257 916 C1

Authors

Krasnjanskij V.P.

Mikhajlov V.V.

Borisevich I.V.

Potryvaeva N.V.

Mel'Nikov S.A.

Timan'Kova G.D.

Dates

2005-08-10—Published

2003-12-04—Filed