METHOD OF PREPARING HETEROLOGICAL IMMUNOGLOBULINS FOR VIRAL INFECTIONS MARBURG AND EBOLA CONTROL Russian patent published in 1997 - IPC

Abstract RU 2089217 C1

FIELD: medicine, virology, biotechnology. SUBSTANCE: method involves immunization of animal-producers with viral antigens prepared from organs of the infected animals (sheep, goats). Blood sampling in animal-producers is carried out at neutralization index 2.0 lg and above and 2.75 lg and above for viruses Marburg and Ebola, respectively. Globulin fractions were prepared from serum blood by alcohol precipitation at negative temperatures followed by globulin purification. The obtained preparation shows low reactivity, apyrogenic and does not induce immunostimulation and immunodepression. EFFECT: improved method of preparing, enhanced quality of immunoglobulins. 6 tbl

Similar patents RU2089217C1

Title Year Author Number
METHOD FOR PRODUCTION OF HYPERIMMUNE SERUM CONTAINING HETEROLOGIC IMMUNOGLOBULINES AGAINST EBOLA FEVER 2016
  • Pyankov Oleg Viktorovich
  • Khromykh Aleksandr Anatolevich
  • Volchkov Viktor Evgenevich
  • Surber Andreas
  • Bodnev Sergej Aleksandrovich
  • Pyankova Olga Grigorevna
  • Agafonov Aleksandr Petrovich
  • Mikheev Valerij Nikolaevich
  • Popova Anna Yurevna
RU2627631C1
LIQUID PREPARATION CONTAINING IMMUNOGLOBULIN EFFICIENT AGAINST MARBURG FEVER FROM HORSE BLOOD SERUM (HORSE IMMUNOGLOBULIN MARBURG) 2003
  • Krasnjanskij V.P.
  • Mikhajlov V.V.
  • Borisevich I.V.
  • Potryvaeva N.V.
  • Mel'Nikov S.A.
  • Timan'Kova G.D.
RU2257916C1
PREPARATION CONTAINING IMMUNOGLOBULIN AGAINST ABOL FEVER FROM HORSE BLOOD SERUM AND LIQUID ABOL IMMUNOGLOBULIN 1996
  • Mikhajlov V.V.
  • Borisevich I.V.
  • Timan'Kova G.D.
  • Krasnjanskij V.P.
  • Potryvaeva N.V.
  • Lebedinskaja E.V.
  • Chernikova N.K.
RU2130318C1
METHOD OF PHYLOVIRUS SUSPENSION CULTURING IN CELL CULTURE ON MICROCARRIERS 1993
  • Tikhonov V.Ja.
  • Kotov A.N.
RU2076905C1
METHOD FOR PRODUCING LIQUID IMMUNOGLOBULIN AGAINST EBOLA FEVER FROM HORSE BLOOD SERUM 2017
  • Popova Anna Yurevna
  • Demina Yuliya Viktorovna
  • Smolenskij Vyacheslav Yurevich
  • Gordeev Evgenij Vasilevich
  • Rozhdestvenskij Evgenij Vsevolodovich
  • Krasnyanskij Vladimir Pavlovich
  • Kutaev Dmitrij Anatolevich
  • Pantyukhov Vladimir Borisovich
  • Chernikova Natalya Konstantinovna
  • Melnikov Sergej Alekseevich
  • Borisevich Sergej Vladimirovich
  • Borisevich Igor Vladimirovich
  • Nimirskaya Svetlana Aleksandrovna
  • Polyanskij Yaroslav Vladimirovich
  • Nazarov Stanislav Viktorovich
  • Timankova Galina Dmitrievna
  • Zverev Aleksandr Yurevich
  • Osin Vladimir Viktorovich
  • Andrus Aleksandr Fedorovich
  • Syromyatnikova Svetlana Ivanovna
  • Shatokhina Irina Viktorovna
  • Sizikova Tatyana Evgenevna
  • Rumyantseva Irina Gennadevna
RU2673546C1
METHOD OF OBTAINING PURIFIED HETEROLOGOUS IMMUNOGLOBULIN AGAINST EBOLA FEVER 2023
  • Rozhdestvenskij Evgenij Vsevolodovich
  • Khmelev Aleksej Leonidovich
  • Melnikov Sergej Alekseevich
  • Nimirskaya Svetlana Aleksandrovna
  • Popadyuk Elena Evgenevna
  • Chernikova Natalya Konstantinovna
  • Mishalova Ekaterina Yurevna
  • Petrov Aleksandr Anatolevich
  • Sizikova Tatyana Evgenevna
  • Lebedev Vitalij Nikolaevich
  • Boyarskaya Natalya Vasilevna
  • Shagarova Natalya Vasilevna
  • Shatokhina Irina Viktorovna
  • Tselikov Evgenij Mikhajlovich
  • Borisevich Sergej Vladimirovich
RU2815252C1
PROCESS FOR MANUFACTURE OF CONCENTRATES OF VIRUSES THAT PROVOKE HEMORRHAGIC FEVER AND POSSESSING IMMUNOGENIC AND PROTECTIVE ACTIVITY 1991
  • Agafonov A.P.
  • Strel'Tsova M.A.
  • Ignat'Ev G.M.
  • Tverdokhlebov A.V.
  • Chepurnov A.A.
  • Kaliberov S.A.
  • Kuz'Min V.A.
  • Chernyj N.B.
RU2029561C1
METHOD FOR PREPARING HIGHLY SPECIFIC HETEROLOGOUS ANTIRABIES SERUM 2006
  • Sitnik Natal'Ja Pavlovna
  • Zagidullin Nail' Vilenovich
  • Israfilov Azamat Gabdel'Akhatovich
  • Enikeeva Lilija Faridovna
  • Mukhacheva Anastasija Vjacheslavovna
  • Shafeeva Rimma Sabirovna
  • Kuntsevich Jurij Gennad'Evich
  • Petrova Irina Ivanovna
RU2322503C1
METHOD OF PREPARING SERA CONTAINING ANTIBODIES RAISED TO MARBURG VIRUS 1995
  • Frolov V.G.
  • Shestopalov A.M.
  • Nikolenko N.I.
  • Vjazunov S.A.
  • Agafonova O.A.
RU2085214C1
RECOMBINANT PLASMID DNA PET21-NPVE CONTAINING NUCLEOLOPROTEIN (NP) GENE OF EBOLA VIRUS AND RECOMBINANT PROTEIN NP-VE, OBTAINED AS RESULT OF EXPRESSION OF NP GENE OF EBOLA VIRUS USING RECOMBINANT PLASMID DNA PET21-NPVE AND POSSESSING IMMUNOGENIC AND ANTIGENIC PROPERTIES 2020
  • Ivanova Alla Vladimirovna
  • Volkova Natalya Vyacheslavovna
  • Chepurnov Aleksandr Alekseevich
  • Demina Anna Vladimirovna
  • Kononova Yuliya Vladimirovna
  • Shcherbakov Dmitrij Nikolaevich
  • Kazachinskaya Elena Ivanovna
RU2739505C1

RU 2 089 217 C1

Authors

Kudojarova N.M.

Kizimov N.V.

Dedkova L.M.

Smolina M.P.

Sergeev N.N.

Dates

1997-09-10Published

1992-04-01Filed