FIELD: medicine, pharmacy.
SUBSTANCE: invention proposes applying oltipraz, i. e. 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione, known early as agent used against schistosomiasis and carcinogenesis for prophylaxis and treatment of liver progressing fibrosis and cirrhosis and for manufacturing a medicinal drug of indicated designation. Also, invention relates to pharmaceutical composition containing oltipraz and a method for its using. Oltipraz exhibits effect on liver and provides protecting effect against hepatotoxicity due to inhibition of producing β-TGF.
EFFECT: valuable medicinal properties of oltipraz and pharmaceutical composition.
6 cl, 4 dwg, 14 ex
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