METHOD FOR PREPARING CETP INHIBITOR, INTERMEDIATE SUBSTANCE AND METHOD FOR ITS PREPARING Russian patent published in 2005 - IPC

Abstract RU 2259355 C2

FIELD: organic chemistry, chemical technology.

SUBSTANCE: invention relates to the improved method for preparing a substance of the formula (IA) that inhibits the protein carrying out the transfer of cholesterol ester. Method involves using the new available intermediate compound of the formula (VIIIA) . Method involves interaction of compound of the formula (VIIIA) with 3,5-bis-(trifluoromethyl)benzyl halide in the presence of a base.

EFFECT: improved preparing method.

10 cl, 9 ex

Similar patents RU2259355C2

Title Year Author Number
METHOD FOR PRODUCING 2-[(3R)-3-METHYLMORPHOLIN-4-YL]-4-(1-METHYL-1H-PYRAZOL-5-YL)-8-(1H-PYRAZOL-5-YL)-1,7-NAFTHYRIDINE 2019
  • Platzek Johannes
  • Rubenbauer Philipp
  • Van Der Haas Hendricus Nicolaas Sebastiaan
  • Hoogeveen Sonja Elisabeth
  • Van Oers Matthijs Cornelis Maria
  • Gieling Reinerus Gerardus
  • Dekker Jeroen Alexander
RU2802512C2
METHODS FOR PREPARING SUBSTITUTED ARYL-CONDENSED AZAPOLYCYCLIC COMPOUNDS, INTERMEDIATE SUBSTANCES AND METHODS FOR THEIR PREPARING 2002
  • Singer Robert Alan
  • Makkinli Dzhejson Dehniel
RU2282619C9
SUBSTITUTED PYRIDINE COMPOUND 2011
  • Nakamura Tsujosi
  • Namiki Khidenori
  • Terasaka Naoki
  • Sima Akiko
  • Khagikhara Masakhiko
  • Ivase Noriaki
  • Takata Katsunori
  • Kikuti Osamu
  • Tsuboike Kadzunari
  • Setoguti Khirojuki
  • Joneda Kendzi
  • Sunamoto Khidetosi
  • Ito Kodzi
RU2572606C2
POLYCYCLIC ANTAGONISTS OF TLR7/8 AND THEIR USE IN TREATMENT OF IMMUNE DISORDERS 2016
  • Sherer, Brajan A.
  • Brugger, Nadya
RU2783748C2
PYRIDINESULFONEAMIDE AND ITS SALTS, HYDRATES AND COMPLEXES WITH -ALCOHOLS USEFUL IN AGRICULTURE, HERBICIDE COMPOSITIONS, METHOD OF STRUGGLE AGAINST WEEDS, METHOD OF STRUGGLE AGAINST FOXTAIL (ALOPECURUS), AN INTERMEDIATE COMPOUND FOR ITS SYNTHESIS 1993
  • Andrea Tehrik Artur
  • Liehng Paul' Khsiao-Tseng
RU2117666C1
METHOD FOR OBTAINING AZETIDINONE COMPOUNDS AND DERIVATIVES OF AZETIDINONE COMPOUNDS 2015
  • Baj Khua
  • Chzhao Syujyan
  • Chzhan Yuntsaj
  • Li Syujfej
  • Chzhan Yun
  • Syuj Dechzhou
  • Chzhan Li
  • Syuj Syaotsze
  • Chzhu Tsifen
  • Van Syaomin
  • Yan Chzhitsin
  • Chzhon Tszekhua
  • Chzhan Tszyan
RU2650687C1
PYRAZOLE COMPOUNDS SUBSTITUTED BY HETEROARYL AND THEIR APPLICATION IN PHARMACEUTICS 2019
  • Miura, Tomoya
  • Hirashima, Shintaro
  • Manabe, Tomoyuki
  • Iida, Tetsuya
  • Sakurai, Kentaro
RU2805312C2
3-AMINOPYPERIDINE DERIVATIVES AND METHODS FOR PRODUCTION THEREOF 2003
  • Ripin Dehvid Garol'D Braun
RU2309147C9
CCR-2 ANTAGONIST SALT 2004
  • Dzhensen Mark
  • Larsen Robert
  • Sidler Dehniel Richard
RU2317295C1
ALTERNATIVE METHODS FOR SYNTHESIS OF RENIN INHIBITORS AND INTERMEDIATE COMPOUNDS THEREOF 2005
  • Zedel'Majer Gottfrid
  • Mikel St'Juart Dzhon
  • Rjueger Genrikh
RU2411230C2

RU 2 259 355 C2

Authors

Dehmon Dehvid Berns

Dagger Robert Uehjn

Skott Robert Uill'Jam

Dates

2005-08-27Published

2002-04-08Filed