FIELD: chemistry.
SUBSTANCE: invention relates to a novel method for preparing an azetidinone compound represented by formula (I). Ketoester of the carboxylic acid represented by formula (II) serves as a starting material and is subjected to Grignard addition, stereoselective dehydration, reduction of the ester group, protection of the hydroxyl group, addition of imine after the condensation with the a chiral auxiliary, cyclization and deprotection to obtain a compound represented by formula. 
EFFECT: present invention has the advantages of readily available raw materials, several synthesis steps, simplicity of operations, high yield, good stereoselectivity and low cost, and can also be used for industrial production.
35 cl, 19 ex
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