FIELD: organic chemistry, medicine, pharmacy.
SUBSTANCE: invention relates to derivatives of pyrazine of the general formula (I):
wherein R1 means hydrogen (H) or halogen atom; R2, R3 and R5 mean hydrogen atom (H); R4 and R6 mean hydroxy-group optionally protected with acetyl or benzoyl group; A means oxygen atom (O); n = 0; Y means oxygen atom (O), or their salts. Compounds show the excellent anti-viral activity and useful as a therapeutic agent in treatment of viral infections. Also, invention describes a pharmaceutical composition.
EFFECT: valuable medicinal properties of compounds and composition.
7 cl, 2 tbl, 15 ex
Authors
Dates
2005-08-27—Published
2001-02-14—Filed