DERIVATIVES OF PYRAZINE AND THEIR SALTS, PHARMACEUTICAL COMPOSITION COMPRISING THESE COMPOUNDS Russian patent published in 2005 - IPC

Abstract RU 2259368 C2

FIELD: organic chemistry, medicine, pharmacy.

SUBSTANCE: invention relates to derivatives of pyrazine of the general formula (I):

wherein R1 means hydrogen (H) or halogen atom; R2, R3 and R5 mean hydrogen atom (H); R4 and R6 mean hydroxy-group optionally protected with acetyl or benzoyl group; A means oxygen atom (O); n = 0; Y means oxygen atom (O), or their salts. Compounds show the excellent anti-viral activity and useful as a therapeutic agent in treatment of viral infections. Also, invention describes a pharmaceutical composition.

EFFECT: valuable medicinal properties of compounds and composition.

7 cl, 2 tbl, 15 ex

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RU 2 259 368 C2

Authors

Egava Khirojuki

Furuta Jousuke

Sugita Dzun

Uekhara Sajuri

Khamamoto Soiti

Jonezava Kendzi

Dates

2005-08-27Published

2001-02-14Filed