DERIVATIVES OF N-HETEROARYLNICOTINAMIDE, INSECTICIDE AND METHOD FOR ITS PREPARING Russian patent published in 2007 - IPC C07D413/12 C07D413/14 A01N43/80 A01N43/836 A01P7/04 

FIELD: organic chemistry, chemical technology, insecticides.

SUBSTANCE: invention relates to derivatives of N-heteroaryl-4-(halogenalkyl)nicotinamide represented by the general formula (I): wherein R represents (C₁-C₆)-alkyl group that can be substituted with one or some halogen atoms; R¹ represents hydrogen atom, (C₁-C₆)-alkyl group that can be substituted with one or some substituted chosen from group of substitutes A, (C₂-C₆)-alkenyl group or acyl group; X represents group of the formula -C-R² or nitrogen atom; each among R² and R³ represents independently hydrogen atom, halogen atom, (C₁-C₆)-alkyl group that can be substituted with one or some substitutes chosen from group of substitutes A, (C₃-C₇)-cycloalkyl group, (C₂-C₆)-alkenyl group, (C₃-C₇)-cycloalkenyl group, formyl group, group of the formula: -CH=NOR⁴ (wherein R⁴ represents hydrogen atom or (C₁-C₆)-alkyl group, cyano-group, phenyl group that can be substituted with one or some substitutes chosen from group of substitutes B, 5- or 6-membered heterocyclic group (heterocycle comprising 1-2 heteroatoms that are similar and chosen from nitrogen atom), (C₁-C₆)-alkoxy-group, (C₁-C₆)-alkylthio-group or phenoxy-group. The group of substitutes A represents group consisting of halogen atom, (C₁-C₆)-alkoxy-group, (C₁-C₆)-alkylthio-group, cyano-group and phenyl group. The group of substitutes B represents group consisting of halogen atom, (C₁-C₆)-alkyl group that can be substituted with one or some substitutes chosen from above given group of substitutes A, (C₁-C₆)-alkoxy-group that can be substituted with one or some substitutes chosen from above given group of substitutes A, or its salt. Also, invention relates to insecticide comprising a derivative of N-heteroaryl-4-(halogenalkyl)nicotinamide or its salt as an active component and a carrier optionally. Also, invention relates to a method for synthesis of derivative of N-heteroaryl-4-(halogenalkyl)nicotinamide. Invention provides synthesis of derivatives of N-heteroaryl-4-(halogenalkyl)nicotinamide possessing the high insecticide activity.

EFFECT: improved method of synthesis, valuable properties of derivatives.

18 cl, 3 tbl, 91 ex