FIELD: biotechnology.
SUBSTANCE: claimed method includes bacteria cultivation of genus Bacillus in broth followed by isolation of collected inosine from cultural liquid. As producer bacteria with resistance to growth inhibition with polymyxin B and/or colistin is used. Also disclosed are method for production of inosine-5'-monophosphate and two new strains of inosine producers: Bacillus subtilis and Bacillus amyloliquefaciens.
EFFECT: inosine production with increased yield.
8 cl, 4 tbl, 3 ex
Authors
Dates
2005-09-10—Published
2002-02-11—Filed