FIELD: chemistry.
SUBSTANCE: invention relates to biotechnology. Inosine is obtained by means of fermentation method which includes growing becteria - producents of inosine in nutritional medium and its isolation from culture broth. As producents mutant strains of bacteria Bacillus subtilis " ВКПМ-8998" and Bacillus amyloliquefaciens "ВКПМ-9789" are used, which are resistant to inhibition of growth by 3,4-dehydro-DL-proline. The obtained mutant strains and the claimed method allow producing inosine with high yield.
EFFECT: elaboration of method for producing inosine with high yield.
3 cl, 3 tbl, 3 ex
Authors
Dates
2008-09-20—Published
2005-09-14—Filed