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2 422 510

(13)

(51)

IPC

C12N1/20(2006-01-01)

C12P19/32(2006-01-01)

C12P19/34(2006-01-01)

C12P19/38(2006-01-01)

C12R1/07(2006-01-01)

C12R1/125(2006-01-01)

(21) (22)

Application

2008138616/10, 2008-09-30

(24)

Start date

2008-09-30

(22)

Actual filing date

2008-09-30

(45)

Published

2011-06-27

(72)

Inventor

Gronskij Sergej ViktorovichRomanenkov Dmitrij VladimirovichZakataeva Natalija PavlovnaAsakhara Takajuki

(73)

Holder

Zakrytoe Aktsionernoe Obshchestvo Institut Adzhinomoto-Genetika" Agri)Adzhinomoto Ko., Ink.

METHOD OF PRODUCING PURINE RIBONUCLEOSIDE AND RIBONUCLEOTIDES Russian patent published in 2011 - IPC C12N1/20 C12P19/32 C12P19/34 C12P19/38 C12R1/07 C12R1/125

Abstract RU 2422510 C2

FIELD: medicine.

SUBSTANCE: method implies using a Bacillus bacterium modified in such a manner that it contains an inactivated gene coding 3-hexulose-6-phosphatesynthase. The method involves cultivation of said bacterium in a nutrient medium. It is followed by recovery of said purine nucleoside from a culture fluid.

EFFECT: invention allows increasing production of purine nucleosides, such as inosine, xanthosine, guanosine or adenosine.

9 cl, 2 dwg, 2 tbl, 4 ex

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RU 2 422 510 C2

Authors

Gronskij Sergej Viktorovich

Romanenkov Dmitrij Vladimirovich

Zakataeva Natalija Pavlovna

Asakhara Takajuki

Dates

2011-06-27—Published

2008-09-30—Filed