FIELD: medicine, clinical laboratory diagnosis.
SUBSTANCE: method involves using carboxylated polystyrene latex spherical particles suspension with immobilized specific polyclonal antibodies raised against antithrombin III on their surface and wherein milk α-casein (antithrombin III-latest) is added as an inert component. Method for assay involves successive fractional plasma dilutions and the concentration of antithrombin III in the parent sample is calculated by the formula. Method provides rapid determination of antithrombin III concentration in blood plasma. Method can be used for diagnosis of pathological states in the blood coagulation system.
EFFECT: improved assay method.
2 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR DETERMINING THE FUNCTIONAL ACTIVITY OF ANTITHROMBIN III IN BLOOD PLASMA | 2021 |
|
RU2772195C1 |
| POLYSTYRENE LATEX-BASE IMMUNODIAGNOSTICUM | 2002 |
|
RU2231366C2 |
| METHOD OF DETERMINING ACTIVITY OF ANTITHROMBIN III IN BLOOD PLASMA | 0 |
|
SU1464090A1 |
| 0 |
|
SU1562859A1 | |
| METHOD OF ANGIOPATHY DEVELOPMENT RISK DIAGNOSTICS IN ARTERIAL HYPERTENSION CASES WITH METABOLIC SYNDROME | 2007 |
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| METHOD OF DIFFERENTIAL DIAGNOSTICS OF HBV- AND HCV-INFECTION IN PATIENTS WITH LIVER CIRRHOSIS | 2010 |
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| SOLUTION FOR CORRECTION OF PRIMARY HOMEOSTASIS DISORDER WITH PLASMA-SUBSTITUTING SOLUTIONS OF NOVEL COMPOSITION | 2005 |
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RU2300385C1 |
| METHOD OF QUANTITATIVE DETERMINATION OF FIBRINOGENS IN BLOOD PLASMA | 0 |
|
SU1146002A1 |
