(S)-METHYL-3-(3-NITROPHENYL)PENTANOATE Russian patent published in 2005 - IPC

Abstract RU 2263106 C2

FIELD: organic chemistry, biochemistry.

SUBSTANCE: invention relates to a new intermediate compound, namely, (S)-methyl-3-(3-nitrophenyl)pentanoate that is used in preparing [R-(R*,R*)]-N-[3-[1-[5,6-dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl-6-propyl-2H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)-2-pyridinsulfonamide representing a protease inhibitor. This inhibitor can be used in treatment of HIV-infected patients. Invention provides preparing new intermediate compound for the new protease inhibitor.

EFFECT: valuable medicinal and antiviral properties of compound.

1 cl, 3 sch, 9 ex

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RU 2 263 106 C2

Authors

Gejdzh Dzhejms R.

Kelli Robert S.

Kh'Juitt Brehdli D.

Dates

2005-10-27Published

1998-09-03Filed