STRAIN COD OF SEVERE ACUTE RESPIRATORY SYNDROME VIRUS OF GENUS CORONAVIRUS DESIGNATED FOR DEVELOPMENT OF AGENTS AND METHODS FOR BIOLOGICAL PROTECTION Russian patent published in 2005 - IPC

Abstract RU 2263144 C2

FIELD: virology.

SUBSTANCE: invention proposes the strain CoD of severe acute respiratory syndrome virus. The strain is isolated from a nasopharynx washing off eluate taken of in a patient. The strain is deposited in the Specialized collection of virus in Virological center NII microbiology of Russian Federation the Defense Ministry at № 1136. The proposed strain is the first isolated strain of coronavirus of IV genotype in Russian Federation region. The strain possesses biological activity in cells Vero E6 = 7.1 lg CPD50 x cm-3. The proposed strain can be used as diagnosticum in IFA-system for determination of antibodies raised against the severe acute respiratory syndrome virus in human blood. Also, the strain can be used as a positive control specimen in PCR-test-system for detection of severe acute respiratory syndrome virus RNA.

EFFECT: valuable properties of virus.

1 dwg, 1 tbl

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RU 2 263 144 C2

Authors

Syromjatnikova S.I.

Pistsov M.N.

Stepanov N.N.

Borisevich S.V.

Merkulov V.A.

Markov V.I.

Onishchenko G.G.

Vasil'Ev N.T.

Maksimov V.A.

Dates

2005-10-27Published

2003-12-17Filed