FIELD: medicine.
SUBSTANCE: invention refers to medical virology and can be used for developing diagnostic techniques and biological protection means. Disclosed is a high-yield strain of the Sindbis fever virus strain 1383 clone 3 virus registered in the State Virus Collection (number of a depositor of SVC No. 1273), recovered from the CNS (from the brain of sick birds - Somateria mollissima and then by sequential genetic cloning), characterized by complete primary structure of envelope proteins (envelop 1 - E1 and envelop 2 - E2) and nucleocapsid (core - C) of virion. Strain has high immunogenic and antigenic activity.
EFFECT: strain of the Sindbis fever virus 1383 clone 3 is a convenient biotechnological model for obtaining diagnostic and vaccine preparations, as well as a genetic vector for applied genetic engineering.
1 cl, 3 dwg, 2 tbl, 3 ex
