LIPOSOMAL COMPOSITION WITH PACLITAXEL FOR TREATING CANCER AND METHOD FOR ITS OBTAINING Russian patent published in 2005 - IPC

Abstract RU 2264807 C2

FIELD: pharmaceutics.

SUBSTANCE: the suggested composition contains phosphatide, cholesterol, amino acids and lyophilized excipient. The composition mentioned contains no polyoxyethylated castor oil and deals with substitution of toxic expensive adjuvant with nontoxic medium and easily obtained adjuvant and could be adapted for industrial manufacturing. The method for obtaining the above-mentioned composition deals with mixing the above-mentioned components, drying and sterilization. Innovation provides low toxicity, good tolerance by a patient, high solubility in water and increased stability due to no aggregation and fall out of crystals.

EFFECT: higher efficiency of application.

13 cl, 14 ex, 2 tbl

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RU 2 264 807 C2

Authors

Vehn Goin

Chzhou Vehj

Chehn Guan

Chehn Pehjjuan'

Dates

2005-11-27—Published

2001-02-28—Filed