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2 266 327

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(51)

IPC

(21) (22)

Application

2004107034/13, 2004-03-09

(24)

Start date

2004-03-09

(22)

Actual filing date

2004-03-09

(45)

Published

2005-12-20

(72)

Inventor

Puzankova O.S.Bajbikov T.Z.Dolganova E.K.Kukushkin S.A.

(73)

Holder

Federal'Noe Gosudarstvennoe Uchrezhdenie Tsentr Okhrany Zdorov'Ja Zhivotnykh" Vniizzh)

TRANSMISSIBLE GASTROENTERITIS OF SWINE VIRUS STRAIN FOR PRODUCTION OF DIAGNOSIS AND VACCINE PREPARATIONS Russian patent published in 2005 - IPC

Abstract RU 2266327 C1

FIELD: veterinary virology and biotechnology.

SUBSTANCE: transmissible gastroenteritis of swine virus strain (TGSV) was isolated by sequential passages on SPEV (swine embryo kidney cell) and other cell cultures. Said virus strain is most effectively cultivated in 3-4-day monolayer of SPEV cells, obtained in roll-tube vessel, wherein after cultivation for 24-30 h infective activity level is 7.5 lg TCD₅₀/cm³. Strain survives starting characteristics for 18-month storage and for 9-10 passages (observation time) on SPEV cell culture.

EFFECT: TGSV strain with high biological, antigenic and immunogenic activity useful in production of high-specific and sensitive diagnosticums and high-immunogenic and harmless inactivated vaccine preparations.

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RU 2 266 327 C1

Authors

Puzankova O.S.

Bajbikov T.Z.

Dolganova E.K.

Kukushkin S.A.

Dates

2005-12-20—Published

2004-03-09—Filed